Biotin and derivatives
Medchemexpress LLC 3H-indolium inner salt (TEA), N-hydroxysuccinimide ester | 1620475-28-6 | 95.0% | 1043.25 | C45H62N4O16S4 | 10 MG
Alexa Fluor 647 NHS ester (TEA) is a far-red, photostable succinimidyl ester dye supplied as the triethylammonium (TEA) salt for covalent labeling of primary amines on proteins, peptides, and amine-modified oligonucleotides. It produces strong fluorescence suitable for fluorescence imaging, flow cytometry, and other fluorescence-based assays. The product is supplied as a blue to dark blue solid and is sensitive to moisture and light.
- Reactive succinimidyl ester for covalent labeling of primary amines.
- Far-red fluorescence compatible with 633-647 nm excitation for imaging and flow cytometry.
- Photostable with high signal intensity for prolonged imaging.
- Suitable for labeling proteins, peptides, and amine-modified oligonucleotides.
- Supplied as a blue to dark blue solid in TEA salt form; store sealed, away from moisture and light.
Medchemexpress LLC Mal-GGG-Bal-NHS ester | 1193111-65-7 | 97.6% | 522.47 g/mol | 5 MG
Mal-GGG-Bal-NHS ester is an ADC linker reagent used to introduce a maleimide-containing GGG-Bal-NHS moiety for conjugation to antibodies or other amine- or thiol-containing biomolecules.
- Used as an ADC linker in antibody-drug conjugate synthesis.
- Contains an NHS ester for amine coupling and a maleimide for thiol conjugation.
- High reported purity of 97.6% for reliable coupling performance.
- Soluble in water at high concentration (50 mg/mL) with ultrasonic treatment if needed.
- Recommended storage under inert atmosphere and cold conditions to preserve stability.
Medchemexpress LLC FP-Biotin | 259270-28-5 | 99.1% | 592.75 | 1 MG
FP-biotin is a potent organophosphorus toxicant, ideal for identifying new biomarkers of organophosphorus toxicants exposure. It quantifies the activity of FAAH, ABHD6, and MAG-lipase. This product is utilized in plasma studies because biotinylated peptides can be easily purified by binding to immobilized avidin beads. It is suitable for identifying organophosphorus toxicants reactive proteins and is for research use only.
- Quantifies FAAH, ABHD6, and MAG-lipase activity
- Used in plasma studies for easy purification of biotinylated peptides
- Suitable for identifying organophosphorus toxicants reactive proteins
- Appears as a white to light yellow solid
- Ships at room temperature in continental US
- Store at -20°C under nitrogen; in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
- Soluble in DMSO (25 mg/mL)
Medchemexpress LLC M-PEG14-NHS ester | 773.86 | 100 MG
M-PEG14-NHS ester is a solid laboratory chemical intended for research use only. It is stable under recommended storage conditions and is not classified as a hazardous substance or mixture. This product is suitable for the manufacture of substances and has not been validated for medical applications.
- Solid appearance
- Stable under recommended storage conditions
- Not classified as a hazardous substance or mixture
- For research use only
eMolecules 1807518-72-4 | Mal-PEG1-NHS ester | Ambeed | MFCD26127783 | 310.262 | C13H14N2O7 | 97.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 5g | 794508519
Mal-PEG1-NHS ester | Ambeed | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 97.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 5g | 794508519
Medchemexpress LLC Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo... | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 g/mol | C56H80N12O9S | 50 MG
Ibrutinib-biotin is a biotin-conjugated chemical probe derived from the BTK inhibitor ibrutinib. It features ibrutinib linked to biotin via a long-chain linker and is designed for target engagement, affinity pull-downs, and assay development directed at Bruton's tyrosine kinase (BTK).
- Biotin-conjugated probe for affinity capture and pull-down assays.
- Derived from a BTK inhibitor for target-specific engagement.
- Low-nanomolar potency against BTK (IC50 0.755-1.02 nM).
- High purity suitable for research applications (>99.6%).
- Available as solid material and as a 10 mM solution in DMSO.
- Molecular weight approximately 1,097.37 g/mol.
![eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169626.jpg-250.jpg)
eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 5X1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Apexbio Technology LLC Sulfo-NHS-SS-11-Biotin 1g
Sulfo-NHS-SS-11-Biotin is an amine-reactive water-soluble biotinylation reagent containing an N-hydroxysulfosuccinimide (Sulfo-NHS) active ester group and a cleavable disulfide bond The Sulfo-NHS moiety reacts specifically with primary amines in proteins peptides or other biomolecules forming stable amide linkages This reagent introduces a disulfide-containing spacer arm enabling subsequent selective cleavage under reducing conditions for release of biotinylated molecules It is commonly employed in affinity chromatography immunoprecipitation experiments cell surface protein labeling and target identification allowing isolation purification or detection of biomolecules through streptavidin or avidin affinity interactions
Medchemexpress LLC DBCO-N-bis(PEG4-NHS ester) | 2639395-38-1 | 96.2% | 995.03 | C49H62N4O18 | 5 MG
DBCO-N-bis(PEG4-NHS ester) is a PEG-based bifunctional linker that contains two PEG4-NHS ester groups and a dibenzocyclooctyne (DBCO) moiety. It is designed for bioconjugation and protein labeling via NHS-ester chemistry and for copper-free click conjugation with azide-containing partners through strain-promoted alkyne-azide cycloaddition (SPAAC).
- Contains two PEG4-NHS ester groups and a DBCO functional group.
- Enables protein modification through NHS-ester conjugation to primary amines.
- Supports copper-free SPAAC click chemistry with azide partners.
- Suitable for small-scale research use; available in 5 mg and larger sizes.
- Molecular weight 995.03; CAS number 2639395-38-1.
Medchemexpress LLC Bis-PEG10-NHS ester | 2221949-02-4 | 95.0% | 752.76 | C32H52N2O18 | 100 MG
Bis-PEG10-NHS ester is a PEG-based linker containing two N-hydroxysuccinimide (NHS) ester groups. It is used as a cleavable linker in the synthesis of antibody-drug conjugates (ADCs) and PROTACs to enable conjugation to primary amines.
- Contains two NHS ester functional groups for amine conjugation.
- Purity typically 95.0%.
- Molecular weight approximately 752.76; formula C32H52N2O18.
- CAS number 2221949-02-4 for unambiguous identification.
- Available in multiple pack sizes, including 100 mg.
- Storage: pure form at -20°C; in solvent store at -80°C for longer-term stability.
Medchemexpress LLC Biotin methyl ester 250mg
Biotin methyl ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research
Medchemexpress LLC Biotin-lc-lc-nhs | 89889-52-1 | 98.0% | 567.70 | C26H41N5O7S | 25 MG
Biotin-LC-LC-NHS is an N-hydroxysuccinimide (NHS) ester biotinylation reagent with dual long-chain spacers. It covalently attaches biotin to primary amines on proteins, antibodies, and small molecules for labeling, detection, or affinity capture. Handle using appropriate safety precautions and store protected from light at -20°C.
- NHS ester reactive toward primary amines.
- Dual long-chain spacers reduce steric hindrance during labeling.
- Molecular weight 567.70 and formula C26H41N5O7S for precise calculations.
- Purity 98.0% for research-grade applications.
- High solubility in DMSO (100 mg/mL) with recommended freshly opened DMSO.
- Store at -20°C, protect from light, and handle under standard laboratory safety practices.
Medchemexpress LLC Azido-PEG16-NHS ester | 00-00-0 | 99.9% | C39H72N4O20 | 10MG
Azido-PEG16-NHS ester is a PEG-based bifunctional linker featuring an azide moiety and an N-hydroxysuccinimide (NHS) ester. It enables conjugation to primary amines via the NHS ester and subsequent click chemistry using the azide, making it suitable for bioconjugation, labeling, and PROTAC synthesis. The reagent is provided at high purity and is soluble in DMSO for convenient formulation.
Medchemexpress LLC (S,E)-TCO-NHS ester | 1610931-22-0 | MFCD24386372 | ≥98.0% | 267.28 g/mol | C13H17NO5 | 10 MG
TCO-NHS ester (axial) is a trans-cyclooctene N-hydroxysuccinimide ester used as an amine-reactive building block for bioorthogonal conjugation. It enables rapid inverse electron-demand Diels-Alder (iEDDA) reactions with tetrazine partners and is suitable for labeling or modifying amine-containing small molecules and biomolecules in organic media. The reagent is supplied as a purified solid with supporting analytical documentation for research use.
- Amine-reactive NHS ester for efficient conjugation.
- Fast bioorthogonal iEDDA reactivity with tetrazines.
- Suitable for labeling and bioconjugation of biomolecules.
- High purity for reproducible experimental results.
- Analytical documentation available (SDS, COA, H-NMR).